In a patient with dysfibrinogenemia, which test result would be normal?

In a patient with dysfibrinogenemia, the immunologic fibrinogen level, which measures the total amount of fibrinogen in the blood, is typically normal. Dysfibrinogenemia refers to a condition where the fibrinogen that is present in the blood is dysfunctional, leading to abnormal clotting, but the overall quantity of fibrinogen is often within the normal range.

Thrombin time, APTT, and PT are clotting tests that evaluate the functionality of the coagulation pathways and are likely to be abnormal in dysfibrinogenemia due to the presence of dysfunctional fibrinogen. In contrast, the immunologic fibrinogen level specifically assesses the concentration of fibrinogen without evaluating its functional properties, which is why it remains normal even in the presence of dysfibrinogenemia.