In primary fibrinolysis, the fibrinolytic activity results in response to:

In primary fibrinolysis, the condition is characterized by the spontaneous activation of the fibrinolytic system without a preceding significant coagulation cascade or the formation of substantial clot. This spontaneous activation occurs due to various factors, such as certain medical conditions or the presence of tissue plasminogen activator (tPA), which can lead to the breakdown of fibrinogen and fibrin. As a result, fibrinolytic activity becomes increased, leading to the degradation of fibrin clots and subsequently, a state where there is an excess of fibrin degradation products.

This contrasts with conditions where there is increased fibrin formation or other scenarios where fibrinolysis is activated as a response to an existing clot or coagulopathy. In primary fibrinolysis, the activation happens naturally and independently, thus making it a distinctive characteristic of this condition.