Which is NOT typically associated with multiple myeloma?

The characteristic features of multiple myeloma include hyperviscosity of the blood, monoclonal gammopathy, and the presence of Bence-Jones protein in the urine. Hyperviscosity occurs due to an excess of immunoglobulins produced by malignant plasma cells, leading to thicker blood and potential complications such as impaired circulation and organ dysfunction. Monoclonal gammopathy refers to the abnormal proliferation of a single clone of plasma cells, which results in an increase in a specific type of immunoglobulin, a hallmark of multiple myeloma. Bence-Jones proteins, which are free light chains of immunoglobulin, are frequently found in the urine of patients with multiple myeloma due to the kidney's inability to adequately filter these proteins when produced in excess.

While osteolytic lesions are indeed a common manifestation of multiple myeloma, they are not the only or exclusive feature of the disease. Osteolytic lesions arise from the overactivity of osteoclasts stimulated by factors released from myeloma cells, leading to bone destruction. However, it's important to recognize that the presence of osteolytic lesions is associated with multiple myeloma rather than being a definitive or sole characteristic of the condition. Overall, the