Which of the following is NOT a characteristic finding in a patient with iron deficiency anemia?

In iron deficiency anemia, one of the hallmark features is an increase in total iron-binding capacity (TIBC) rather than a decrease. TIBC tends to increase as the body attempts to maximize iron uptake due to low iron stores.

Microcytic, hypochromic red cell morphology is a defining characteristic of iron deficiency anemia, reflecting the smaller size and paler appearance of red blood cells that arise from insufficient hemoglobin production. Additionally, decreased serum iron and ferritin levels are indicative of diminished iron stores and availability in the body, commonly seen in this type of anemia. Similarly, increased RBC protoporphyrin can occur, as the synthesis of hemoglobin is compromised due to inadequate iron.

Overall, the increase in TIBC is a physiological response to iron scarcity, making it the correct answer to identify as not characteristic of iron deficiency anemia.