Which type of acute myeloid leukemia is known as true monocytic leukemia?

Acute monocytic leukemia is characterized by the predominance of monoblasts in the bone marrow and peripheral blood, marking it as a form of leukemic transformation specifically focused on monocytic lineage. This type of leukemia demonstrates the clinical and cytological features associated with monocytic cells, which include the proliferation of immature forms of monocytes. It is significant for its unique clinical manifestations, such as infiltration of tissues with a high number of monocytic cells, which can affect the patient's overall health and outcomes.

In the context of acute myeloid leukemia, while the other types like acute myeloid leukemia, minimally differentiated, and acute myeloid leukemia without maturation have their distinctions primarily based on cellular characteristics and maturity levels, they do not specifically identify as true monocytic leukemia. Acute myelomonocytic leukemia also includes myeloid and monocytic cells but is distinct in that it does not exclusively comprise monocytic cells. Therefore, the defining characteristics of acute monocytic leukemia make it the correct response to this question, highlighting its specificity to monocytic lineage within acute myeloid leukemia classifications.